Clinical Case Reports, Research & Trials ISSN : 2581-6756
Bipasha Bose

Yenepoya Research Centre

Yenepoya University


Journal Short Name - CCRRT


Dr Bipasha Bose obtained her Ph.D. degree in Applied Biology (Molecular Carcinogenesis) from Advanced Centre for Treatment, Research and Education in Cancer, Tata Memorial Centre, Navi Mumbai, India in 2004. She has a more than 11 years of post-PhD research experience working in Stem Cell Biology, in academia and industry in India, Belgium and Singapore. Dr Bose holds key skills in the field of clinical, as well as, R and D grade stem cells. Her noted contributions to the field of regenerative medicine involve her co-work with the scientists for deriving human embryonic stem cells (hESC) for the first time from the Indian subcontinent, differentiation of hESC into functional insulin producing β islets and their pre-clinical translation, differentiation of hESC into functional hepatocytes. She has also contributed in the field of adult stem cell biology and proven the myogenic potential of aged muscle stem cells and perivascular mesenchymal stem cells, hepatocyte differentiation from Multipotent Adult Progenitor cells. Her contribution in the field of basic biology of stem cells has proven the pluripotent conversion of myostatin- null muscle stem cells without using reprogramming factors. She has contributed to several publications and book chapters as the lead author in the peer-reviewed journals and books of international repute. Dr. Bose also has two patents to her credit. Currently, Dr Bose is working in Yenepoya Research Centre, Yenepoya University. Her present focus is on establishing R and D scale human and mouse stem cell laboratories, guiding Ph.D students in her area of expertise of basic biology of stem cells and stem cell therapy for diabetes, liver diseases and muscle disorder, and also various aspects of ocular stem cells.

Reasearch Interest

Pluripotent stem cells, Adult stem cells such as Muscle derived stem cells (MDSCs), pluripotent conversion of MDSCs without growth factors or small molecules. Differentiation of PSC into pancreatic beta islets and hepatocytes. Limbal stem cells and its role during UV/bright light induced oxidative stress.

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